THE BASIC PRINCIPLES OF KETAMINE EFFECTS

Most clinical research settle for the role of drugs modulating as a result of NMDA receptors. Ketamine is noncompetitive voltage-dependent NMDA-receptor channel blocker whose antidepressant action is evident at very low doses, and with escalating doses, it mimics psychotomimetic action and inevitably contributes to anesthesia in higher doses.[4]Thr